讲座题目：From Gene Loss to Rediploidization: The Role of Polyploidization in Plant Genomic Diversity and Adaptation
主 讲 人：Zhen Li 助理教授
主 持 人：李勤 副教授
Dr. Zhen Li is an Assistant Professor at Ghent University. He honed his expertise during his PhD and postdoctoral work with Prof. Yves Van de Peer. Dr. Li's research employs comparative genomics and phylogenomics to unravel the complexities of plant genome evolution, particularly in the context of ancient polyploidizations and their role in plant adaptation and diversification.
Polyploidization, known as whole-genome duplication (WGD), is an important evolutionary process in plants. While the majority of flowering plants display remnants of ancient polyploidization, influencing evolutionary innovations and species adaptability, the focus has traditionally been on gene duplication. Recent genomic studies, however, have gradually unveiled the crucial role of gene loss in plant evolution. Rediploidization, a process where polyploid genomes evolve towards a diploid-like state, critically shapes plant genome evolution. This phase is characterized by significant gene loss, a key aspect of genomic reorganization. Understanding the dynamics of rediploidization requires a thorough exploration of the mechanisms behind this gene loss. Among these mechanisms, pseudogenization is particularly notable. By focusing on the role of pseudogenization in the context of gene loss during rediploidization, we aim to decipher its contribution and significance to provide deeper insights into how different mechanisms, including pseudogenization, collectively influence the genomic landscape post-WGD. Furthermore, accurately contextualizing gene loss within rediploidization processes requires precise identification of WGD events, a challenge compounded by the complexity of plant genomic data and the need for versatile analytical tools. To address these challenges, we have developed a comprehensive methodology and user-friendly tool for polyploidy inference. This tool not only facilitates more accurate WGD analysis but also broadens the scope of research in plant genome evolution, emphasizing the dynamic interplay of gene loss, duplication, and rediploidization in shaping the diversity and adaptation of plant species.